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According to this model, a multigene family can expand as a consequence of gene duplication and contract because of gene loss (e.g. as a result of unequal crossover).
A lower pressure in the surrounding brain would allow the arterial wall to expand as a consequence of a sudden increase in blood pressure leading to tissue damage at high/low pressure interphases.
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The population expanded as a consequence of there being more to consume than there was before.
The available niches are likely expanded as a consequence of AMD3100-induced mofilization of recipient's residual bone marrow cells from marrow niches, allowing a competitive advantage for the healthy donor cells.
One study showed that FOXP3+Treg are rapidly recruited into tumour sites and expanded as a consequence of triggering through self-antigen reactive TCR (Darrasse-Jeze et al, 2009).
Studies in Arabidopsis and rice suggest that the kinase family has largely evolved as a response to biotic stress and has greatly expanded as a consequence of adaptation to fast-evolving pathogens (Hanada et al. 2008; Jacquemin et al. 2014).
Bacteria that had expanded as a consequence of vaccination all belonged to the merged cluster or a single distinct cluster containing mostly Prevotella, unclassified Bacteroidetes, Fusobacterium, Streptococcus, and Neisseria spp. (cluster 8).
Conversely the under-representation of TRAV26 (and TRDV1) genes in the expressed TRA repertoire suggests functional selection through TRA chain expression has not been a primary factor in replication of these homology units, but rather supports the concept that some TRAV subgroups have been expanded 'collaterally' as a consequence of being within the same homology units as TRDV1.
Additionally, we do not have data confirming that the same γδ-T cell clone actually expanded as a direct consequence of repeated infliximab infusions.
This includes the huge pentatricopeptide repeat gene family that likely expanded in angiosperms as a consequence of one or more waves of retrotransposition by retro-TEs (O'Toole et al. 2008).
To check whether R. balthica has already expanded its range as a consequence of ongoing climate change as suggested for freshwater benthos [ 74], we analysed the publicly available long term database of the Swedish University of Agricultural Sciences (SLU) (available at http://www.ma.slu.se) with canonical correspondence analysis (see Additional File 4).
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Justyna Jupowicz-Kozak
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