This ROS increase originates from several sources, both exogenous (ultraviolet radiations, trauma, stress, infections, malignancies, certain drugs) and endogenous.
Disseminated life-threatening disease and endogenous endophthalmitis are generally seen in immunocompromised patients; however, immunocompetent individuals can also be affected with exogenous endophthalmitis from trauma.
The dematiaceous fungus P. richardsiae has rarely been implicated in human disease but has been described in one case of exogenous endophthalmitis following trauma with a retained intraocular foreign body [14].
They are not reliable in the detection of acute exogenous osteomyelitis as, after trauma, there is always the scintigraphic presence of a lesion and it is not possible to differentiate between fracture and bone infection.
Defects in the system most likely can be induced by endogenous (e.g. constitutional, genetic) factors, or exogenous factors, such as trauma, deficient nutrition, brain damage, etc,; or a combination of both.
Taking together, it is speculated that endogenous spermidine accumulated in retinal glia may be an initial resource for RGC survival, and if such resources are depleted due to aging and trauma then exogenous spermidine may protect RGCs.
Capsular contracture results when the normal healing process fails or when a pathological change is initiated by tissue trauma or an exogenous trigger.
This study was designed to investigate the protective effects of exogenous hydrogen sulfide (H2S) on trauma-hemorrhagic shock (T-H).
It is usually exogenous in origin, occurring after ocular trauma or surgery [2, 3].
The mechanism of injury in this case is most likely due to a traumatic exogenous source in the setting of trauma.
