Our results shed light on processes of exogenous mRNA trafficking, which are crucial to estimate the mRNA bioavailability, and increase the biosafety of transgene integration mediated by transposition.
Practically, the evaluation should account for the uncontrolled environment, e.g. general (long-term) accident trends, exogenous changes in traffic volumes, and for the selection bias (regression-to-the-mean) if relevant.
This study also highlights the benefit of using exogenous visual cues in traffic signs to capture drivers' attention.
We have utilized this nuclear targeting of VT to design a unique delivery system which transports exogenous DNA via vesicular traffic to the nucleus.
The SEM method treated the overall distress index as a latent variable while various distresses were treated as endogenous and other influence factors such as age, layer thickness, material type, weather, environment and traffic, were exogenous observed variables.
Furthermore, we perform a thorough numerical evaluation of the derived results with respect to their behavior in response to changes in exogenous parameters like the traffic specifications of the flows or the configuration of the network.
Altogether, these initial studies establish that some exogenous resident Golgi enzymes traffic between separate Golgi populations in fused cells.
We also evaluated the traffic of exogenous LDL-[BODIPY-Cho] in infected macrophages isolated from LL biopsies (Virchow's cells) by confocal analysis.
Further, DCs but not macrophages can cross-present antigen of apoptotic cells to T cells because they express αvβ5 integrin, which plays a critical role in the trafficking of exogenous antigens [31], [32].
Trafficking of exogenous Tac and Tac-FCHO1 fusion proteins in HeLa cells.
