Sentence examples for exogenous mechanical from inspiring English sources

To explore if the exogenous mechanical environment is enough in itself to regulate PSC activity, a physiomimetic model representing soft and stiff tissues was produced.

Actin depolymerization through Rho GTPases or exogenous mechanical tension has been suggested as a key determinant for the formation of astrocyte stellation.

Bone formation in response to exogenous mechanical loading is dependent on prostaglandin synthesis by the inducible isoform of cyclooxygenase, COX-2.

This finding suggests that derived hESC-CMs have not adequately matured, at least as far as energy metabolism, and so may benefit from exogenous mechanical or electrical stimulation in order to upregulate energy-related pathways prior to transplantation.

Consistent with the importance of mechanical signals to maintain the osteogenic potential of bone marrow cells, superposition of exogenous mechanical signals onto normal daily activities can enhance bone at both the cellular and tissue levels [9] [11] with exercise promoting osteoblastogenesis and inhibiting adipogenesis [12].

17- 19 The activities of actin modulating proteins 20 are also influenced by endogenous cell contractile force 21 or exogenous mechanical stimuli.

Indeed, in the absence of exogenous factors, mechanical compression increased NO production at 5 and 20% oxygen tension and the loading-induced catabolic response was reduced at 1% in porcine cartilage explants [ 21].

In conclusion, we have developed a versatile methodology for engineering cardiac tissues with a near-adult functional output without the need for exogenous electrical or mechanical stimulation, and have identified mTOR signaling as an important mechanism for advancing tissue maturation and function in vitro.

In conclusion, we have developed a versatile methodology for engineering cardiac tissues with a near-adult functional output without the need for exogenous electrical or mechanical stimulation, and have identified mTOR signaling as an important mechanism for advancing tissue maturation and function in vitro.

Exogenous CGRP increased mechanical sensitivity in a greater proportion of joint nociceptors in the MIA-treated rats than in the saline-treated rats.

A limitation of this study is our use of an engineered NP model, which lacks an exogenous biological response, mechanical loading, and other physiological factors.