Sentence examples for exit checkpoint from inspiring English sources

WEE1 and CHK1, which regulate the G2 exit checkpoint by inactivating the CDK1-cyclin B complex [43], [44] are maximally destabilized at ∼12 24 h in the V600E lines A375 and LOX-IMVI, and this loss likely allows cells to exit G2 and inappropriately enter M.

Gates were closed and barriers put up at all entrance and exit checkpoints, and the military police turned away all but essential personnel.

But residents said the city remained under a tight siege, with government loyalists running exit checkpoints and shooting at anyone who approached.

PRDX-1 and Chk2 were activated in a dose-dependent manner after 2 and 5 Gy in the HF66 wt and HF66 ctrl shRNA cells, which subsequently exited checkpoint, while HF66 NG2 shRNA failed to show dose-dependent PRDX-1 and Chk2 induction (Supplementary Figure ESM 2c).

Human osteosarcoma cells also enter mitosis with γ-foci, suggesting that human cells are able to exit the checkpoint arrest and divide before the damage has been fully repaired.

In this way, they avoid the problem of exiting the checkpoint associated with the autocatalytic cytoplasmic amplification model, since the kinetochore has more direct control over the amplification.

However, a nonubiquitylatable Cdc20 mutant where all lysine residues had been replaced with arginine was recently shown to have little difficulty in exiting spindle checkpoint arrests [36].

She didn't want to be searched by a male soldier and went back to exit from the checkpoint".

However few studies assessed the expression of the principal cyclin regulating checkpoint exit, cyclin D1.

PSCS is generally considered a sign of mitotic exit and spindle checkpoint dysfunction.

Once the kinetochore is silenced by microtubule attachment, the dissociation activity rapidly reactivates Cdc20 to permit checkpoint exit.