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From a national defense, as well as a civilian infrastructure perspective, a need exists to design and develop systems resilient to disruption.
With the expected replacement of deteriorated reinforced concrete bridges to occur in the next several decades, an opportunity exists to design more economic bridge columns in seismically active regions which are rapidly constructed while having enhanced crack resistance for extended service life.
An urgent need exists to design more effective therapies.
8 23 A need exists to "design out" violence from sex work.
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In engineering many optimization approaches exist to design macroscopic machines.
A wide range of possibilities exist to design combined heat and power plants.
Two approaches exist to design an IT2FLS: the first approach is partially dependent and based on a type 1 FLS design and then a translation to the IT2FLS.
Moreover, studies in which the enormous need have existed to design desired futures in natural disaster management have increased as well.
While algorithms exist to design metabolic network reduction strategies for aligning these objectives, the biochemical basis of the growth-product coupling has remained unresolved.
Thanks to recent progress made in particle physics, compact and efficient solutions now exist to design and construct portable telescopes which can be operated under the difficult field conditions encountered on tropical volcanoes.
At a clinical level, there is currently no evidence to suggest that oxaliplatin provides an additional benefit to concurrent chemo-radiation regimes that utilise fluoropyrimidines; we evaluate the reasons for this observation, the limitations of clinical trial design and the opportunities that currently exist to design clinical trials which are underpinned by an understanding of the basic biology.
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