Sentence examples for existing spindle from inspiring English sources

In addition the agent appeared to have an improved therapeutic ratio compared to existing spindle poisons and is well absorbed when administered orally.

To study if chromosome alignment process per se is asymmetric, we inhibited the Centromere-associated Protein E (CENP-E), the kinetochore-bound kinesin that aligns polar chromosomes by transporting them along existing spindle microtubules (Wood et al., 1997; Kapoor et al., 2006; Barisic et al., 2014).

This is mediated by augmin, a complex of 8 proteins, which recruit γTuRC along existing spindle MTs and leads to the formation of new MTs, increasing the speed and stability of spindle assembly (Goshima et al., 2007; Goshima et al., 2008; Lawo et al., 2009; Uehara et al., 2009; Zhu et al., 2009).

Overall, existing data suggest spindle orientation influences asymmetric cell fate though it does not strictly determine whether or not a division will be asymmetric or symmetric.

Specifically, we build a phosphorylation network centered on the human checkpoint protein BUB1B and show that it provides a different, but complementary view of the spindle checkpoint from existing protein interaction network building tools.

The reduction in the number of nuclei within the embryo sac may be due to the anomalies during the cell division process, such as the failure of mitosis, the fusion of mitotic spindles or the degeneration of existing chalazal nuclei (Yeung and Law 1997).

In experiments of angiogenic sprouting, a single cell is initially shown to branch out in a spindle-shaped fashion from an existing vessel [ 41- 43].

As such, many studies are being carried out on automatic variable preload control methods that apply a preload to a spindle rolling bearing as an alternative to the existing fixed position preload and constant pressure preload methods.

Single-point tools, gripped in a boring head attached to a rotating spindle, are moved circularly against the sides of the existing holes.

They reported that the major type of canal shape for the IC is Y-morphology, with four other types - spindle-shaped, very large, cystic, and narrowed - existing as minor types [22].

This allows for machining at spindle speeds that are more representative of those used in existing machine tools.