NUMTs may also increase the efficiency of pre-existing origins, as it could be the case for NUMTs located close to or within ARS.
Thus NUMTs can act as independent origins, when inserted in an appropriate genomic context or affect the efficiency of pre-existing origins.
In conclusion, most NUMTs are located in regions identified as origins of replication where they are either positioned far from ARS and may act as independent origin elements as it seems to be the case for NUMT2 and NUMT28, or are located close to ARS and may act as elements that strengthen or affect pre-existing origins.
Genotyping of these variants in existing African origin sample sets coupled to measurements of urine albumin excretion levels should reveal which is the most likely functional candidate for albuminuria risk.
Being a totally new creation with no pre-existing origin story, people were eager to see what shape this mythic sci-fi event would actually take.
Apparently, these genes are of an ancient origin existing before the divergence of the three kingdoms.
These Presocratic speculations combined naturalistic myths of origins with the workings of chance-like processes to create a naturalistic account of the origins of existing forms of life (see the entry ancient atomism).
There are four main hypotheses concerning their origins, and existing evidence is such that there is a lack of overwhelming support for any one of them.
Already, experts in biogeochemistry — the study of the scientific underpinnings of earth's origins and existing biosystems — are working with social scientists to study the impact of rapid urbanization on plants and animals.
The existing literature on the origins of wildlife conservation in Africa has portrayed the formation of protected areas as an imposition of colonial state authorities.
An overview of the existing models for the origins of translation and coding shows that none of them, not even the attractive triplicase model, offer a complete, compatible with the Continuity Principle outline of the path to the Protein Breakthrough.
