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Therefore, no safety margin at existing exposures has been identified (Chiodo et al. 2004; Koller et al. 2004).
Miranda's research focuses on identifying interventions that will prevent harmful environmental exposures in children, rather than mitigating existing exposures that may have already affected children.
In addition, there had to be substantial existing exposures in Britain and/or cases of cancer still occurring due to past exposures.
Several non-cancer diseases have appreciable background incidence in the population (e.g., cardiovascular effects, respiratory effects, reproductive effects), and the exposure to a particular chemical being assessed adds to existing exposures to other toxic chemicals.
With the recent evidence demonstrating an inverse association between blood lead levels and cognitive function in children exposed to low levels of lead, there is no safety margin at existing exposures.
However, a recent study on a cohort of children whose lifetime peak blood levels were consistently < 10 μg/dL has extended the association of blood lead and intellectual impairment to lower levels of lead exposure and suggests there is no safety margin at existing exposures.
Similar(52)
It is conceivable that at that time, due to the high SO2 levels, hypertrophication-indicating species could not yet exist despite already existing exposure to nitrogen compounds.
Existing exposure to such projects will be gradually reduced, it added.
They are simply too busy managing existing exposure for now to be interested in new issuing governments.
The letter, which was coordinated by campaign group ShareAction, stresses that HSBC must adopt a "clear, timebound plan" to phase out its existing exposure to the dirty fuel.
Depending on the basis of the actual algorithms, most of the existing exposure models can be broadly classified as physical-based, statistical-based, and rule-based models.
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