Existing expert-knowledge can be used to filter data in various ways before calculating associations, thus reducing the number of proposed tests and the multiple testing burden based on a biologically-driven rationale.
The obvious advantage of MDR over the traditional methods of repeat masking and expert annotation is its lower time and pre-existing expert knowledge requirement, as no repeat databases have to be constructed and de novo repeat annotation (which is inherently time-consuming and labour-intensive) becomes fast and easy.
Existing expert systems for hydraulic system design use production rules as its source of knowledge.
The EFs we used to adjust for under-reporting were estimated on the basis of several data sources, including existing literature, expert knowledge, and laboratory evidence.
Model parameters were set by integrating existing research and expert knowledge.
In this second validation scenario, we consider a collection of manually curated pathways based on expert knowledge and existing literature obtained from the Kyoto Encyclopedia of Genes and Genomes (KEGG, http://www.genome.jp/kegg/pathway.html).html
AquaMaps outputs compare well to the existing methods tested, and inclusion of expert knowledge results in a general improvement in model outputs.
AquaMaps is a bioclimatic envelope model that combines existing point occurrence data with available expert knowledge on species occurrence in environmental and geographic space to generate large-scale predictions of the relative occurrence of marine species.
Base Existing taxonomies, literature review and expert knowledge 5 (GSE, location, legal entity, geographic distance and temporal distance) Facet-based Qualitative Objectively described Based on expert judgment, comparison with existing taxonomies and demonstration of utility by classifying GSE literature.
We encourage parties to draw on prior experience, existing knowledge and ongoing knowledge by national authorities and expert authorities to guide experts working on gene drives," Burt said.
