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In this mini-review, we would like to examine the evidence that currently exists regarding the questions raised above, suggest a different interpretation of the existing clinical trial data, and offer our viewpoint as to the controversies that exist in the current ADA guidelines.
Accordingly, many research groups and clinical consortia have postulated modifications and unifications of existing clinical trial designs.
Modifying the existing clinical trial model will lead to a more accurate evaluation of the safety and efficacy of bevacizumab and other biological agents in treating metastatic cancer.
To make Vivli more appealing as a resource for researchers, the project will try to aggregate the trial information from all existing clinical trial data platforms and help direct researchers on where and how to request data from them.
The existing clinical trial model does not allow for modification of chemotherapeutic doses in a manner that maximizes the effect of biologic response modifiers and does not account for its "chemosensitizing" effect.
Existing clinical trial data on proning may not be generalizable to patients receiving high PEEP.
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If the findings of existing clinical trials hold up in future research, the potential consequences of this deficiency are likely to go far beyond inadequate bone development and excessive bone loss that can result in falls and fractures.
Existing clinical trials have shown that topical corticosteroids are often effective in the management of oral lichen planus (OLP).
There are no trial data directly comparing stroke risk with varying types and doses of estrogen as existing clinical trials were based on single regimens of HRT.
Although it might be possible to answer some of these questions with longer follow-up of existing clinical trials, randomised controlled trials with new study designs will be needed.
The latest word on meditation's effects comes from a meta-analysis--essentially a study of existing clinical trials that sifts, consolidates and distills their findings.
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