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The large number of patients required, the length of time the study must run, existing accepted follow-up practices in different countries, and the difficulty of managing patients on different follow-up strategies within the same centre all pose problems for the design of a randomized trial.
Constructivist case studies always seem to result in the support of existing, accepted theory (Pickering 1984a; 1991b; 1991; Collins 1985; Collins and Pinch 1993).
This large nationwide study in Turkey of pupils aged 6 17 years has shown that many children and adolescents have a headache type that does not conform to existing accepted diagnostic criteria.
The foot print of existing, accepted track circuit is the reference and the safety function of any other solution will be compared with this and the characteristics, in terms of safety, will be improved based on this comparative assessment.
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Finally, even existing and accepted guidelines will not be used unless they are available in clinical situations; a computerized order entry system with integrated decision support should be available to every doctor referring patients for imaging.
The principles governing the use of laboratory animals as laid out by the Federal University of Technology, Minna Committee on Ethics for Medical and Scientific Research and also existing internationally accepted principles for laboratory animal use and care as contained in the Canadian Council on Animal Care Guidelines and Protocol Review were duly observed.
The instrument has previously been translated into Norwegian according to existing internationally accepted guidelines, and has shown satisfactory results regarding validity and reliability, although the social domain has represented a challenge [ 21, 22].
This is not necessarily an objection to mitochondrial replacement, because the same could be said of the existing widely accepted alternatives – such as refraining from having children or using an egg donor.
Since the move from conventional practice to GRIP constituted an organizational and logistic change that aimed to improve existing and accepted medical practice, approval by the medical ethical committee or patient consent was deemed unnecessary.
The existing clinically accepted serum marker for ovarian cancer is CA-125, which, despite its widespread use for monitoring therapeutic response, is not sensitive or specific enough for early diagnosis.
To address these concerns, we conducted a field-based assessment to identify other assessment tools used to compile data on the availability and functionality of health services in disrupted health sectors, and to evaluate the comprehensiveness of HeRAMS using existing and accepted standards for humanitarian emergency response.
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CEO of Professional Science Editing for Scientists @ prosciediting.com