As the BMDL assumes equal sensitivity within the population studied, current guidelines [ 28, 29] require that the BMDL be divided by an uncertainty factor of 10 to take into account the existence of subjects with increased vulnerability.
29, 30 In sum, the existence of subjects who are CSF A β42 positive but PET A β negative warrants further study, especially long-term longitudinal studies with repeated biomarker assessments, to learn whether the lowering of CSF A β42 precedes PET positivity, or whether other factors underlie this discrepancy in amyloid biomarker outcome.
This will provide, in each subject, the S ISP time course during several months and will allow testing for the existence of subject-specific S ISP daily patterns and correlation of such variation with lifestyle and other factors.
Margaret Gilbert's On Social Facts (1989) made a forceful case for the existence of "plural subjects", a crucial metaphysical thesis that provides one possible foundation for group-oriented, or collective, social epistemology.
But according to the strictures applying to an Aristotelian science no science can probe the existence of its subject matter, but rather must take it as given from a higher science (in this case, metaphysics).
We can't directly verify the existence of other subjects of experience or what is given to them in their experience.
The existence of affected subjects showing mixed phenotypic features and concurrent PrPSc types has been reported but with inconsistencies among studies in both results and their interpretation.
I am also pleased that, in the reports before us and in the agreement we concluded with the Council, we have managed to ensure the continued existence of national quality marks - subject, of course, to the proviso that these national marks actually enhance consumer protection and are not misused or misinterpreted for protectionist purposes.
He cites Aristotle's distinction between demonstrating the existence of some subject, and going on to demonstrate properties of that subject by appeal to the essence of the subject as cause of those properties.
So there are two demonstrative stages in any science, the demonstration of the existence of the subject (quia), and the demonstration of the properties of the subject through its essence (propter quid).
Our memory now has a different function: it is an index, it remembers the existence of a subject and what are the best leads to find information on that subject.
