Given the large amount of BDNF protein in the central nervous system and its role in neurotransmission, a number of researchers have postulated the existence of a role for the BDNF gene (BDNF) in the pathogenesis and treatment response of different neuropsychiatric conditions, including depression, anxiety, and ADHD [ 24– 26].
Altogether these findings strengthen the notion that the expression of miR-221 and miR-222 needs to be tightly regulated during differentiation and suggest the existence of a role of these miRNAs both in progression of myogenic differentiation and in achievement of the differentiated phenotype.
In conclusion, the best explanatory model for our results and those previously published would be the occurrence of a substantial structural change of the PTEN protein, which would preclude its activity as phosphatase and would establish the existence of a role not previously described for this tumor suppressor.
This resulted in a significant reduction in neurosphere size from dissociated ANSCs, suggesting the existence of a role for autophagy during ANSC expansion (Supplementary Figure S2A).
To our knowledge, this is the first report suggesting the existence of a role for pulse oximetry in the assessment of newly diagnosed lung cancer patients receiving palliative anticancer therapy.
The existence of a role of authority for the head of the family.
However, the existence of institutional roles with internal relations to other institutional roles does not entail a holistic account of social institutions.
The finding suggests the existence of redundant roles among members of the miR-195 family and reveals the critical role of this family for neurotoxin-mediated apoptosis or neural cell degeneration in human NPCs.
Difficulties also arise due to existence of discrete roles for each of the domains (educator, manager, care coordinators for example) that make up the single role of the Nurse Consultant [ 24].
However, the existence of such roles for CsZIK proteins in cucumber and specific motif 10 in CsZIKs associated with their specific roles have yet to be studied.
