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This is due to the existence of high throughput technologies like the GeneChip® Human Mapping Array from Affymetrix coupled with the abundant and uniform distribution of SNPs throughout the human genome [ 2- 6].
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The existence of high-throughput methods for assaying SNPs is continually reducing the cost of genotyping and is making these high-throughput methods accessible to more researchers.
However, it can provide guarantees in terms of high throughput.
They are treading cautiously, given the failure of "high throughput screening" in the early 2000s to improve efficiency by using robots to test millions of compounds.
An important limitation of high throughput techniques is the high quality requirements of starting RNA.
Although the existence of a genetic component for allergy was first described almost 100 years ago, progress in gene identification has been hindered by lack of high throughput technologies to investigate genetic variation in large numbers of subjects.
23 In the initial years of high-throughput sequencing, scientists embraced the new technology and hence discovered the existence of the "rare biosphere".
One interesting direction is the application of high-throughput sequencing technologies to the characterization of hundreds of 'epigenomes' (epigenetic marks across the entire genome).
Summary of high-throughput sequencing samples.
This requirement of high-throughput phenotyping techniques limits the throughput of mutant selection gene detection.
Network topological properties of high-throughput yeast two-hybrid screens.
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