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Further examinations show that they are unexplained by FBA and MOMA simply because of the incompleteness of the reconstructed metabolic networks, limitations of the metabolic models (e.g., lack of connection to regulatory and signal transduction networks), and existence of environments difficult to simulate (e.g., temperature changes) (supplementary tables S1 and S2, Supplementary Material online).
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It also provides further evidence for the existence of obesogenic environments for children.
Electrochemical characterizations of these samples evidenced two redox processes assigned to the existence of different environments around Mn4+ in LSM in good agreement with the peaks observed by temperature programmed reduction (TPR).
Another important issue is the existence of an environment populated by dynamic elements, e.g., fleets of mobile robots.
On the other hand, considering the existence of competitive environment, suppliers have to offer customers incentives like discounts and enhance the quality of their products in a competition with other manufacturers.
One potential explanation for opposing findings may be found in the existence of gene-environment interactions.
The existence of gene-environment interactions may explain the discrepancy of results obtained in individual genetic association studies.
These findings indicated the existence of inflammatory environment during infection and egg laying by the schistosome worms.
Another concern is that the existence of additional environment sources of zinc that may have contributed to the overall intake of zinc.
Searches were extended to the lamprey and lizard genomes but contiguous sequences were too small to confirm the existence of gene environment conservation.
In this Perspective, we describe the rationale and evidence relating to the existence of gene-environment and gene-treatment interactions in type 2 diabetes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com