Sentence examples for existence of dose from inspiring English sources

One approach to improve drug response is by increasing dosages beyond the typical dose to increase the efficacy, but this is not an available approach due to the existence of dose limiting toxicities.

First, the existence of dose thresholds cannot be proven or disproven based on experimental observation because measured effects themselves have a limit of detection that will obscure the observation of a threshold, if it exists [ 33].

Mercury exposure will modulate the response, qualitatively through the existence of dose-related thresholds for autoimmune response and quantitatively as increasing doses cause increasing autoimmune response.

The responses to the questionnaire showed that half (50%) of the radiographers were aware of the existence of a dose indicator on the equipment and used its displayed value to monitor the dose to the patient following the mammography procedure.

Application of the LNT hypothesis in the low dose range may lead to an overestimation of the risk in case of the existence of a dose threshold or an underestimate in case of cooperative multicellular radiation effects such as bystander effects.

These results have borderline significance for the existence of a dose effect.

The data from the yeast haploinsufficient proteins supports the 'balance hypotheses' as well as the existence of strong dose sensitivity of this organism.

To conclude, evidence from this cohort suggests the existence of a dose response relationship between maternal glucose concentrations during pregnancy and the fat and lean mass of prepubertal offspring.

The existence of a dose-response then becomes important because there is little point recommending a higher daily dose unless this will result in greater benefit.

Existing human clinical data on elicitation of the food allergic response very clearly show the existence of threshold doses.

Thus, this study provides no information about the existence of a dose-response relationship between drug use and adverse perinatal events.