This diversity, combined with the large number of potentially acetylable lysines on histones, suggested the existence of a specific regulatory mechanism based on the substrate specificity of HATs.
The imperfect correlation between pre- and post-mortem findings illustrates that existing diagnostic tools do not always provide 100% certainty about the existence of a specific disease entity [ 5].
Colby and Chamberlin (1969) presciently concluded that the high degree of specificity of the induction process was consistent with the existence of a specific intracellular receptor, most probably a protein.
Moreover, the low levels of variability present in the PKR-BD, and more specifically in the ISDR, are probably due to the existence of a specific sequence involved in response to interferon [18], [29], [50], [51].
Specifically, regulation 5 (4) (g) and (h) talk about "the price or the manner in which the price is calculated" and "the existence of a specific price advantage".
If there is an error, even a puzzling metaphysical one as to the actual existence of a specific bottle, it is invariably the retailer's boob, not the column's.
He said forensics scientists often will not take steps to search for existence of a specific compound unless an individual overdoses near drug paraphernalia, or there is other environmental evidence.
Previous studies have shown that major depressive patients may differ in several features according to gender, but the existence of a specific male depressive syndrome remains controversial.
In particular, the novelty of the present study is that it explores the existence of a specific cerebral area involved in the recognition of irony versus deceit.
The etiology of this common condition is incompletely understood and the existence of a specific entity of fibromyalgia is still a matter of debate.
Structure activity relationship analysis suggests the existence of a specific target molecule for ATL cell-selective inhibition of proliferation through G2 arrest.
