However, a great deal of interest exists for the further development of in vitro based toxicogenomics methods, for an examination of their potential applicability in the regulatory arena, and for an appraisal of their potential for contributing to improvements in animal welfare.
Scope appears to exist for the exploration of further lines of supporting evidence individually and, perhaps, in combination.
Further restrictions exist for the origin of bovine products (e.g. adeps bovi, brain extract, marrow extract, or neural extract).
Based on increased understanding of the precise mechanisms of gastric acid secretion at the level of receptors, enzymes, and cytoplasmic signal transduction systems, further possibilities exist for the development of effective antisecretory pharmacotherapy.
Greater problems exist for Sunderland further up the pitch.
The overall effects, however, vary among cell lines, expression systems, and the product of interest, and opportunities exist for further enhancement of the cold shock effect on recombinant protein production in mammalian cells [ 12].
Although local delivery to the lung has led to significant progress towards minimising side effects associated with systemic exposure, additional opportunities exist for further enhancement of the therapeutic index.
When a face core interface crack approaches a tri-material wedge, as it may happen at a sandwich core junction, two options exist for further crack advance; one is for the interface crack to penetrate the wedge along the face core interface, and the second is deflection along the core junction interface.
The newer methods now available and the opportunities that exist for further advances are considered.
Given the various definitions that exist for patient engagement, further theoretical and definitional work may be needed to fully develop what constitutes an 'engaged patient' and to measure it reliably.
