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The requirement for many different genes to achieve the full level of AOX in mitochondria suggests that complex pathways of expression exist for the enzyme.
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In the case of HydE, for which structures exist of the enzyme in both SAM-bound and dAdoH/methionine-bound states, greater distortion of the Fe S cluster is observed in the latter case due to the pseudooctahedral coordination of methionine to the unique iron ion.
The maintenance of genetic integrity demands not only that enzymes exist for the synthesis of DNA but that they function so as to ensure the replication of the genetic information (encoded in the DNA to be copied) with absolute fidelity.
Beta oxidation converts fatty acids to acetyl-CoA inside the mitochondria, while various enzymes exist for the conversion of specific amino acids into pyruvate, acetyl-CoA or directly into particular citric acid cycle intermediates.
Although the structure of the isolated monomeric enzyme remains unknown, several crystal structures exist for the RAF kinase domain in complex with ATP-competitive RAF inhibitors.
Various writing systems exist for the language.
Estimates do exist for the three species.
Electrochemical detectors already exist for the job.
Several peripherals exist for the SG-1000 series.
In contrast, lesions in isogenic acapsular S. uberis 0140J mutants were confined to the hasA and hasC open reading frames suggesting no redundancy existed for these enzymes [ 64].
A similar situation may exist for other enzymes that contain dihydrolipoamide dehydrogenase, such as pyruvate dehydrogenase, but their capacity for O2− production seems to be less than that of αKGDH [ 106].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com