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Does there exist a loop of size 100?
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Given that TEL-PDGFRB also induced a large number of IFN-regulated genes including Gbp1, it is tempting to speculate that there may exist an autocrine loop of IFN-γ, and that this in turn induces the transcription of Stat1 and Gbp1.
When direct and indirect evidence exists (i.e. a loop of evidence in the network diagram), inconsistencies between the ORs and intervals of these two sources may arise.
On the other hand, there exist a number of feedback loops, such as from almost any step of the process to data modeling.
There exist a positive feedback loop in the activation of microglia via TNF-alpha; this may be involved in the prolonged activation of microglia [ 15].
Since a cause always precedes its effects, a loop of self-causation does not exist.
However, whether there exists a feedback loop on the activity of AMPK is still unknown.
Just blank walls, a loop of thoughts.
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