Exact(6)
Additionally, other data indicate that antisense DNA exhibits efficacy in vivo when administered at the relatively high concentration of 5 mM (Whitesell et al. [1991]).
A promising result emerging from this study is that ospemifene exhibits efficacy in breast chemoprevention comparable to that of tamoxifen.
As such, p28 is a prototype molecule that exhibits efficacy in patients with advanced (Stage IV) p53wt,mut solid tumours (Warso et al, 2013).
Together, these data confirm that FF/VI exhibits efficacy 24 h after the previous dose and provides additional protection to AHR compared with FF or VI alone.
Drawn upon the above research findings, the isoquinoline-type alkaloid berberine has beneficial effects for blood glucose control in the treatment of type 2 diabetic patients and exhibits efficacy comparable with that of conventional oral hypoglycaemics.
Empagliflozin (BI-10773) is a novel, potent, and selective SGLT2 inhibitor that exhibits efficacy in animal models of diabetes and is currently in development for the treatment of type 2 diabetes.
Similar(54)
Human induced pluripotent stem cells (hiPSCs), which have the ability to differentiate into several cell types1, are promising cell sources and have already exhibited efficacy in experimental models2,3,4,5.
Salvianolic acids and tanshinones both exhibit efficacy in treating idiopathic pulmonary fibrosis (IPF), but their formulation limits their clinical use.
Here we describe our methodology of multi-step mAb screening focused on identifying mAbs exhibiting efficacy and specificity in labeling mammalian brain samples.
Research efforts are now focused on understanding the mechanism of action of these immunotherapies, identifying new inhibitory mechanisms that could be targeted to achieve responses in patients with refractory cancers, and developing approaches that might exhibit efficacy against "immunologically inert" tumors.
We also describe why our emphasis on extensive validation of large numbers of candidates by immunoblotting and immunohistochemistry against brain samples is essential for identifying those that exhibit efficacy and specificity in those applications to become NeuroMabs.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com