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Protein kinase B (Akt/PKB) is an important regulator of cellular metabolism and survival, but it is unclear if aged muscle exhibits alterations in Akt function.
The SV-L1CAM variant exhibits alterations in the molecular structure N-terminal of the Ig1 region and in the cytoplasmic tail as compared to the full-length L1CAM molecule.
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Senescent cells are viable, but exhibit alterations in phenotype and altered gene expression patterns [ 2- 5].
Barr, A. M., Fish., K. N., Markou, A. & Honer, W. G. Heterozygous reeler mice exhibit alterations in sensorimotor gating but not presynaptic proteins.
A key unanticipated finding in this study is that SCOP/PHLPP1 KOs exhibit alterations in baseline and post-injury physiology which may be important.
Another NIAAA-funded study evaluated whether healthy individuals at increased familial risk to develop alcohol dependence exhibit alterations in NMDA receptor function.
Furthermore, diabetic mice exhibited alterations in the expression of Bax and Bcl-XL, and subsequently pathological alterations in the architecture of the bone marrow, pancreas, thymus, and spleen.
Roll bonding is of interest as a method for grain size refinement; oxide-containing materials have increased strength, enhanced work-hardening behaviour, and exhibit alterations in recrystallisation behaviour.
Background: Acquired immunodeficiency syndrome (AIDS) patients exhibit alterations in the metabolism of iron that lead to increased deposition of this element in the tissues.
In contrast, males receiving DOX + CYP injections did not exhibit alterations in spatial memory relative to baseline or males receiving vehicle.
As described above, cancer cells exhibit alterations in the regulation of cholesterol homeostasis and de novo synthesis in the mevalonate pathway.
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