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A series of tertiary amine derivatives exhibiting potent HIV-1 protease inhibiting properties were identified.
Annonaceous acetogenins are a large class of naturally occurring polyketides exhibiting potent anticancer activities.
Recently, a novel glycosylated diphyllin derivative 11 which exhibiting potent anticancer activity by targeting topoisomerase IIα was reported by our group.
Both series were chirally stable with 5,5-series 10 and 45a e exhibiting potent in vitro activity against a range of CAC1 cysteinyl proteinases.
As a result of re-optimization of lead compound 2, we identified novel compound 25a exhibiting potent inhibitory activity against HSL enzyme and cell with high selectivity for cholinesterases (AChE and BuChE).
A common two-ring scaffold, NB82, present in the majority of compounds exhibiting potent biological activity, was used as a generic immunization hapten for the immunization of two rabbits.
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Jabara, she said, "exhibits potent antihistamine properties".
Both compounds exhibit potent anti-oxidative and anti-inflammatory properties3,21,22,23,24,25,26.
Flavonoids exhibit potent anti-neoplastic properties.
Many of the synthesized compounds exhibited potent cytotoxic activity.
Most compounds exhibited potent activity against GSK-3β.
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