Remarkably, these analogues also exhibit enhanced activity, suggesting that activity may correlate with stability.
As expected, compared to their free enzyme mixture system without the chimeric scaffolding, the resulting multienzyme complexes exhibited enhanced activity (~2.4-fold) on wheat straw as a complex cellulosic substrate [116].
Much progress has been made in reducing the Pt loading by alloying Pt with transition metals such as Co, Ni, Cu, etc., as not only is less Pt wasted in the core, but the Pt-based alloys (PtM) often exhibit enhanced activity and durability compared to pure Pt.
Compounds 7a and 7d exhibited enhanced activities against MGC-803 in vitro, when compared to 5-Fu.
Moreover monoclonal antibodies expressed in such plants with specifically altered N-glycosylation exhibited enhanced activities (Cox et al. 2006; Schuster et al. 2007; Strasser et al. 2009; Forthal et al. 2010).
The electro-catalysis measurements towards oxygen reduction reaction indicate that PtCuNi nanocrystals, when loaded on high surface area carbon black, exhibit enhanced activity compared with binary PtCu nanocrystals.
Consistent with the negative regulatory role of KEAP1 in NRF2 activation, KEAP1-KD cells exhibited enhanced transcriptional activity of NRF2 under nonstressed conditions.
Given that most single-agent therapies have limited activity in patients with malignant gliomas, we examined whether AdsTRAIL could exhibit enhanced antitumor activity in combination with agents currently in use or in trials against gliomas.
Here, we examined whether a combination of two cytotoxic drugs with unrelated action mechanisms, DOX (genotoxic) and gamitrinib (mitochondriotoxic), would exhibit enhanced anticancer activity without aggravating unwanted side effects.
Electrodes formed in PVP-containing solutions are found to exhibit enhanced electrocatalytic activity towards NO3− electroreduction at the potentials close to the reversible hydrogen electrode.
And the re-CNFs modified glass carbon electrode (re-CNFs/GCE) exhibits enhanced electrocatalytic activity of about 8 times than the GCE to the oxidation reaction of dopamine.
