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Slides exhibiting defects such as missing or damaged spots were discarded.
Most notably, DNMT1 mutants were isolated from an insertional mutagenesis screen for ES cell clones exhibiting defects in MMR (Guo et al. 2004).
For selected lines exhibiting defects in Rh1 accumulation in the live imaging screening, the immunocytochemical distribution of Rh1 was investigated to evaluate the phenotype with respect to transport and morphogenesis (Table 2, Satoh et al., 2013).
Each composite image was examined in detail to determine the number of seminiferous tubule cross sections and the number of tubules exhibiting defects, including vacuoles, abnormal or degenerating germ cells, immature germ cells in the lumen, and significant germ cell loss.
While this concept is supported by the presence of pathogens in lungs of patients exhibiting defects in mucus clearance [ 6– 8], the roles of the primary defects (airway surface liquid dehydration, dehydrated/concentrated mucus, lack of ciliary beat, decreased mucus clearance) in establishment of chronic inflammation are not fully appreciated.
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In the hepatobiliary phase, the tumor exhibits defects in enhancement (f).
The tumor exhibited defects in enhancement in the hepatobiliary phase (Fig. 2f).
Thus, the joints fabricated using STC and TAC tool exhibited defects in the stir zone.
To circumvent this safeguard against oncogene-driven neoplasia, cancer cells with deregulated MYC frequently exhibit defects in apoptotic pathways.
At restrictive condition, the rna14-11 mutant cells exhibit defects in cell cycle progression with high level of septation.
Ozz−/− mutants exhibit defects in myofibrillogenesis and myofiber differentiation.
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