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Several low molecular weight inhibitors exhibiting activities in the micromolar range could be identified as starting points for structure-based design.
Numerous food-derived peptides exhibiting activities such as opiate, antithrombotic, anticancer, antihypertensive, immunomodulation, mineral-binding, antimicrobial or antioxidant properties have been reported (Hartman and Miesel 2007).
Three categories were established: 'known toxins', 'other possible venom molecules' or 'cellular proteins' for proteins with best hits to well-known scorpion venom toxins, proteins with hits to non-scorpion toxin sequences exhibiting activities compatible with toxic venom action, and other products related to cellular functions without evidence of being toxins, respectively.
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Additionally, we detected several bacterial strains exhibiting activity towards aryl-substituted dihydropyrimidines.
It is notable that nine extracts exhibited activities in both assays.
These antibiotics exhibit activities against Lactobacillus case as well as some strain of Mycobacterium and Streptococcus.
However, none exhibited activity.
All catalysts exhibit activity towards dry reforming of methane.
ω-TA Ml0107 exhibited activity to β-phenylalanine, 1-aminoindane and benzylamine.
LacB exhibited activity after expression in the pET22b vector but it is not satisfying.
In addition, rubrolide F (120) exhibited activity with bacterial strains E. coli (15 µM).
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