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Notably, CgPAD exhibited sequence similarity to PAD1 (YDR538withith less than 14% identity and essentially no homology with FDC1 (YDR539W) isolated from S. cerevisiae[Clausen et al. 1994, Mukai et al. 2010].
In addition, large-scale small RNA sequencing confirmed the occurrence of the expected 21-nt miR319e-GFP species and other 22- and 24-nt species that exhibited sequence relationships with the expected amiRNA.
Additionally, about 0.3% of the Enz+pyrosequencing unmapped reads exhibited sequence identity to an unknown member of the Bacillus genus.
This sequence was compared to similar sequences within the human genome including expressed sequence tags; the retrieved sequences exhibited sequence similarity of greater than 90% to ERVWE1 (Figure 1B) but none encoded the full open reading frames homologous across the full length of ERVWE1.
The CAD promoter regions exhibited sequence identity of 96% for the first 2.5 kb.
Exons of this transcript exhibited sequence identity between human and chimp, but not in more distant primate genomes.
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When possible, all twelve Drosophila species were used for the EvoPrint analysis, while species that exhibited sequencing gaps were excluded.
A panel of fully or partially sequenced entire genomes was searched by BLAST for elements exhibiting sequence similarity to Sinbad.
In addition, circRNAs also exhibit sequence conservation.
Plasmodium vivax thrombospondin-related anonymous protein (PvTRAP) is a promising malaria vaccine candidate; however, it exhibits sequence heterogeneity.
T cell epitopes that exhibit sequence variation may not be subject to the same evasion mechanisms, and hence vaccines that include such variable epitopes may be more efficacious.
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