Suggestions(1)
Exact(18)
Eight of the eleven patients exhibited reactivity to at least one of the predicted epitopes.
Some cultures exhibited reactivity against peptide-pulsed T2 cells (Melan-A or gp100) but not against autologous melanoma or HLA-A*0201+ HLA-A*0201+ll lines.
For example, MAb 5-1 exhibited reactivity reductions to all six fusion peptide double mutant VLPs and also for one of three E311 substitutions.
While some of the reactions were specific for several alleles (e.g., reactions 016 and 018 in the HLA-A locus), other reactions exhibited reactivity with only few (e.g., reactions 008 and 009 in the HLA-A locus) or a single allele (e.g., reactions 001 and 003 in the HLA-A locus) (Table 7, Table 8 and Table S1).
In one case, the lymph nodes exhibited reactivity rather than metastasis.
Indeed, a significant proportion of the anti-PM/Scl-positive patients also exhibited reactivity to the topo I autoantigen (35.1%).
Similar(41)
COOMe-HNE and COOMe-ONE (squares) exhibited reactivities similar to those of their parent compounds (triangles), while COOH-HNE and COOH-ONE (circles) were slightly less reactive.
We demonstrate that these reagents exhibit reactivity similarly as wortmannin and react with members of the phosphatidylinositol 3-kinase and PI3-kinase related kinase families in cellular lysates.
With highly electron withdrawing perfluoroalkyl substituents, oxaziridines exhibit reactivity more similar to that of dioxiranes than typical oxaziridines.
Antisera against the conjugate were prepared and were found to exhibit reactivity toward rhTNF-α by performing ELISA and western blotting (Figure 1C, 1D).
However, these agents exhibit reactivity also toward other aa residues and particularly cysteine.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com