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Whereas the peptide phosphorylated at the second Ser/Thr residue [PPPSPx(p S; Fig. 2A] exhibited only a marginal inhibitory effect at 100 µM, the peptide phosphorylated at the first Ser/Thr [PPP(p SPxS; Fig. 2A] exhibited a strong inhibitory effect close to that of the dually-phosphorylated peptide (Fig. 2A).
Breast cancer specimens (T) with unmethylated ID4 promoter exhibited only a marginal decline (FC = 1.1) in ID4 mRNA expression.
However, BDE47 exhibited only a marginal effect on the alternative splicing events of zebrafish larvae despite seriously affecting its transcriptome.
Although native endostatin exhibited only a marginal inhibition of LS174T tumour growth, P125A-endostatin treatment resulted in significantly enhanced antitumour activity.
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In principle, if a loading parameter is relevant for nonlinear behaviour, the dependency of site amplification as a function of this loading parameter should exhibit only a marginal dependency on other parameters such as magnitude, or distance or frequency contents.
Germline cells transfected with pEGFR-GFP showed only a marginal increase in their cell survival following cisplatin treatment, while cells expressing GFP (pEGFP-N3) exhibited a slight decline in cell survival.
4-Chloro-7-bromomethylbenz(a)anthracene exhibited only marginal activity in that it slightly increased the risk of liver tumour development in male mice.
Differences between those who were and were not admitted to in-patient wards were analysed by chi-squared tests for categorical variables, and independent samples t-tests for continuous variables, including skewed variables, as comparison with a non-parametric alternative exhibited only marginal differences in p-values.
In contrast, wild-type and LYS1 KD plants exhibited only marginal chitinase activities.
Imatinib (0.2 μM) and Dasatinib (2 nM) exhibited only marginal effect on proliferation of Ba/F3 carrying the native Bcr-Abl.
However, the first principal components of the correlation coefficients between signal values and post-mortem intervals exhibited only marginal inter-tissue consistencies (data not shown).
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