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Although CeMn itself exhibited only a low activity for the direct decomposition of NO into N2 and O2, CeMn modified with alkali or alkaline earth species exhibited significant activities.
This absence of incorporation was not due to the modification of the protocol since the incorporation obtained in a sibling experiment that omitted RNase A addition but included a one hour incubation period at 37°C exhibited only a low decrease in the TCA precipitable cpm (Fig. 2C).
Raab and his colleagues found that the primary cells'proliferation, spindle assembly and apoptosis exhibited only a low dependency on Plk1 in contrast to the addiction of many cancer cell lines to the non-oncogene Plk1 [ 11].
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However, the 177Lu-DOTA-PEG5k-Lys-BN 177Lu-DOTA-PEG5k-Lys-BN 177Lu-DOTA-PEG5k-Lys-BN 177Lu-DOTA-PEG5k-Lys-BN 177Lu-DOTA-PEG5k-Lys-BN
In the adult tissues, the results showed that all of these HarmIR genes were strongly expressed in antennae of both sexes except for HarmIR75p.1 and 75p.2 exhibiting only a low level of expression.
There are two reasons for this choice of approach: 1) the bacterial diterpene cyclases mentioned above exhibit only a low level of overall sequence similarity, whereas the GGDP synthases from these bacteria display more than 30%% identity, and 2) a GGDP synthase gene is located near a diterpene cyclase gene in the genomes of these bacteria.
In the deoxyferrous state both of the distal histidine mutants exhibit only a single αβ band with a low intensity shoulder at higher wavelength in comparison to the WT which has two distinct peaks.
Finally, the most promising compounds have drug-like properties and exhibited only low cytotoxicity towards a MRC-5 cell line.
In contrast, Nox1, Nox2, and Nox5 DH domains exhibited only very low NADPH-dependent electron transferase rates (<1 min−1), regardless of the electron acceptor, and no activity was observed using NADH as the electron donor (data not shown).
Fecal samples were taken from 4 of the 6 animals with the lowest hematocrit for McMaster's Quantitative Fecal Egg Counts; 2 of the 4 were negative for parasite detection, while the other 2 exhibited only very low levels (<100 eggs/gram of Trichostrongyles) of intestinal parasites.
We did not use mMSC for the knockdown experiment as protein expression of HIF1 α in mMSC was very low under normoxia) and the cells exhibited only low transfection efficiency.
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