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DMI acute treatment activated GMPE expression only at the lower doses and these responses exhibited modified parameters.
Of the mutants analyzed here, only G113D showed a significant reduction in conductance, although several mutants exhibited modified pressure sensitivity.
Of these 235 genes, a total of 95 exhibited modified expression in response to heat treatment, either presenting increased (52) or decreased (43) expression.
The PSD spectrum of the modified peptide exhibited modified fragment ions b2 (287), corresponding to a modified Pro-1−Thr-2 frandent, and b4 (551), corresponding to the modified Pro-1−Thr-4 fragment.
The enzyme exhibited modified traits: the activity of the purified enzyme was reduced to 49%, the ratios of hydrolytic activities with cephalexin, phenylacetamide or 6-nitro-3-phenylacetylamidobenzoic acid (NIPAB) to penicillin G increased and the enzyme showed a better synthesis/hydrolysis ratio for the synthesis of cephalexin.
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Although trees in polluted areas often exhibit modified growth habits, the immediate causes of changes in crown architecture and their consequences for persistence of plant populations in disturbed habitats are not well understood.
Matrix mineralisation has also been reported to influence terminal osteoblast differentiation into osteocytes and we have also explored whether hypomineralised bones in Phospho1 KO mice exhibit modified osteocyte lacunar and vascular porosity.
From the results obtained, we sorted the genes exhibiting modified expression into five groups showed in Table S1.
A second SQT1 hERG channel gain-of-function pore mutation (Thr618Ile; 'T618I' located in the channel pore-helix), which also exhibits modified inactivation kinetics, has recently been reported [32].
We predict that the remaining probes, which have shorter, or no, accessible sequences, will exhibit modified binding behavior, and we plan to conduct experiments to characterize this behavior.
After a single round of error-prone PCR, the variant Pro15Ser exhibiting modified substrate specificity was generated.
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