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Only one CIMP + Hypo region exhibited consistent levels of significant correlation with expression across all 12 cancer types, located at the 3′UTR of gene PLCL1.
We also examined methylation status at the REX1 locus in previously published human ESCs and iPSCs from Ziller et al. (2011), and found that although all ESC lines examined exhibited consistent levels of low methylation at the REX1 promoter, human iPSC lines analysed in exhibited either hemi- or hyper-methylated REX1 promoter regions.
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In addition to the common extant applications of hEB, aggregates generated via these methods exhibit consistent levels of symmetry and self-organization not attainable using more traditional methods, laying the foundations for a new paradigm of in vitro tissue-level differentiation.
The IFNγ response from patient to patient showed the highest variability among the cytokine responses, even though paired cultures from individual patients exhibited highly consistent levels of STAT1 activation by IFNγ.
In contrast, females in both species exhibited consistent group-level preference of the left forelimb.
Birds' choices also exhibited consistent species-level differences.
These animals exhibited consistent upregulation of Avp mRNA expression, along with increased basal levels of CORT and enhanced CORT release in response to stress.
It exhibited consistent degrading capabilities of 30 kg waste.
Eleven of the EST sequences exhibited consistent sequence differences from LBAC and CSV1.
The intersection of the two group comparisons identified 499 transcripts exhibiting consistent changes in expression levels in all classes of aberrant astrocytes, including trisomic BG01V APCs (G), glioblastoma samples (N) and CCF-STTG1 astrocytoma cells (D) relative to normal, diploid H9 APCs (C).
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