Although the former clinical trial exhibited benefits in the secondary endpoints of hemodynamic improvement, improvement in skin ulcers, and decreased pain [ 8], the latter clinical trial reported increased peripheral edema as well as no benefits in secondary endpoints such as DeltaPWT, the ankle-brachial index, claudication onset time, and quality-of-life measures [ 9].
61, 93 Some studies showed evidence that the anti-Alzheimer agents exhibit benefit to POAG patients.
Third, because the CDK4/6 inhibitor is independent of ER signaling, even models that are completely resistant to endocrine therapy would still exhibit benefit [ 70, 72, 73].
They propose a relay selection scheme that exhibits benefits with respect to energy efficiency.
Although folic acid supplementation shows a potentially modest benefit in stroke prevention, it does not seem to exhibit benefits in connection with preventing CHD and CVD [ 56, 60].
It exhibits benefits in improving some motor functions like the stand balance [ 4], finger force [ 5], and bimanual coordination [ 6] and also subserves the motor function rehabilitation for the patients with brain disorders of Parkinson disease [ 7], brain damage [ 8], chronic stroke [ 9], and so forth.
Children with many stereotypic behaviors, assumed to be an effect of a larger repertoire of automatic reinforcers, exhibited less benefit from treatment.
The prognostic nomogram including CRP exhibited improved benefit over the entire range of threshold probabilities.
In contrast, LN229 H114, producing high levels of 2-HG, exhibited no benefit.
For example, patients with independent activation of mTOR via low levels of the tumour suppressor LKB1, an mTOR inhibitor, exhibited greater benefit from everolimus [ 39].
