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The Financial Accounting Standards Board now sets accounting rules and has exhibited backbone.
Both MIMs exhibited backbone amide proton chemical shift perturbations upon titration of N-labeled IST1303-366 with ULK3 MIT 2, indicating that both IST1 MIMs can contact ULK3 MIT 2, whereas the upstream IST1 residues 303 317 were not perturbed.
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If you've ever worked for someone who doesn't exhibit backbone, you understand the risk.
The resulting structure may exhibit severe backbone clashes at the dimeric interface depending on the backbone dissimilarity between the target and template proteins.
In agreement with our backbone dynamics data for helix 3, this region also exhibits elevated backbone B factors in the crystal structure of E. coli acyl-ACP (12).
We hypothesized that a successful computationally designed sequence would have backbone structure and dynamics characteristics similar to that of the input structure and that, in contrast, domain-swapped dimers would exhibit increased backbone flexibility and/or altered structure in the hinge-loop region to accommodate the large conformational change required for domain swapping.
Foldamers are peptide and nucleic acid inspired oligomers which exhibit major backbone alterations.
These residues also exhibit large backbone B factors in crystal structures of E. coli acyl-ACP (12).
In contrast, the BDTy-2TVTDPP with 4,8-substituted BDT unit in backbone exhibited better solubility, deeper HOMO energy level and more smoothed blend film morphology.
The polymer with fluorene unit and bulky phenylene-substituted benzene unit in the backbone exhibited the highest PL efficiency among these neutral and quaternized PPVs.
In contrast, under alkaline conditions heparin-bound catB exhibited much smaller backbone fluctuations (2 Å) than the very flexible apo form in these conditions.
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CEO of Professional Science Editing for Scientists @ prosciediting.com