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All compounds exhibited affinity for CB1 and CB2 receptors.
Generally, the study compounds exhibited affinity for both the A1 and A2A adenosine receptors.
Using in silico docking methodology, these were evaluated to determine those that exhibited affinity for the AMP binding site.
Due to its structure, cyclopentanone exhibited affinity to the active adsorption sites on alkyl chains as well as to the polar, uncovered surface of the adsorbent.
Surface plasmon resonance based studies suggested that while pep14 exhibited affinity to human and rabbit IgM, pep14 failed to interact with mouse IgM.
Among the molecules tested, only yangonin exhibited affinity for the human recombinant CB1 receptor with a Ki = 0.72 μM and selectivity vs. the CB2 receptor (Ki > 10 μM).
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Most of investigated compounds exhibited affinities for α1-ARs, 5-HT1A, 5-HT7 (Ki ∼ 0.8 353 nM) significantly higher than those for 5-HT6 receptors.
When substituted for Chlamydomonas in the live-cell ELISA, none of these algae exhibited affinities above background levels (i.e., affinities exhibited by VHH BoNT/B).
A random peptide library was generated for fusion to the N-terminal of EGF, and polypeptides exhibiting affinity were selected in vitro by ribosome display.
The sputtered chrome-gold layer is known to exhibit affinity with thiophenol molecules [7, 8].
(c) Carboxyl groups ending in -COOH cause GOS surface to exhibit affinity for NH2 end of protein.
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