In addition, circRNAs also exhibit sequence conservation.
Only in slowly evolving species (e.g., coelacanths) does tetherin exhibit sequence similarity to one potential sister gene.
T cell epitopes that exhibit sequence variation may not be subject to the same evasion mechanisms, and hence vaccines that include such variable epitopes may be more efficacious.
Gadd45 proteins exhibit sequence homology to the L7Ae/L30e/S12e superfamily [19].
Interestingly, this epitope, unlike other HLA-B57-restricted epitopes, is never found to exhibit sequence variation as a consequence of viral escape in previous studies [34].
Finally, Selenophosphate Synthetase 1 and 2 (SPS1 and SPS2), which exhibit sequence similarity, catalyse the formation of mono-selenophosphate, the donor compound of Selenium necessary for the synthesis of selenocysteine.
In the present study, the identified SGIV miRNAs exhibit sequence variations frequently, and two classes of variants that comprised of 5' and 3' terminal variability were found, as with iso-miR [27], [50].
The Polo-like kinases (Plks) are a family of serine/threonine kinases that exhibit sequence identity in both their N-terminal catalytic domain and their C-terminal region, which is termed the polo-box domain (PBD).
We blasted the mouse genome with this partial sequence and found a 344-bp region and a 379-bp region that exhibit sequence homology (69% and above) with Asxl1 and Asxl2 transcripts, respectively.
Two allelic families of Mac have been identified in S. pyogenes; Mac I and Mac II [87] exhibit sequence divergence in the middle third of the proteins (∼50% amino acid identity in this region).
Many exhibit sequence similarity in all 17 species (not shown).
