Exact(7)
Salvianolic acids and tanshinones both exhibit efficacy in treating idiopathic pulmonary fibrosis (IPF), but their formulation limits their clinical use.
We also describe why our emphasis on extensive validation of large numbers of candidates by immunoblotting and immunohistochemistry against brain samples is essential for identifying those that exhibit efficacy and specificity in those applications to become NeuroMabs.
In the SC-10-JCK model, in spite of VEGF expression, bevacizumab did not exhibit efficacy.
Small molecule activators of SIRT1 have been identified that exhibit efficacy in animal models of diseases typically associated with aging including type 2 diabetes.
A reversible MetAP-2 inhibitor was also reported to lead to endothelial cell cycle arrest and to exhibit efficacy in a range of murine tumour models [ 17].
The folate antagonist pemetrexed has been shown to exhibit efficacy against non-squamous cell lung cancers [ 3], and is currently used in combination with cisplatin as a standard treatment regimen for patients with non-squamous cell lung carcinoma.
Similar(53)
Additionally, other data indicate that antisense DNA exhibits efficacy in vivo when administered at the relatively high concentration of 5 mM (Whitesell et al. [1991]).
All plants identified through the literature review of traditional Chinese medical texts and through ethnobotanical surveys exhibited efficacy as anti-insulin resistance agents.
Here we describe our methodology of multi-step mAb screening focused on identifying mAbs exhibiting efficacy and specificity in labeling mammalian brain samples.
Six of the nine medicinal plants identified through the literature review exhibited high or moderate anti-insulin resistance bioactivity in this study while five of the seven medicinal plants identified through the ethnobotanical surveys exhibited efficacy in the study screenings.
Liquid-formulated 1-MCP strongly delayed ripening in both tomato and avocado fruit, and in tomato fruit exhibited efficacy comparable to that of gaseous 1-MCP (SmartFreshSM Quality System) applied at 500 nL L−1 for 9 h.
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