Seven compounds were found not only to be hypocytotoxic toward intestinal epithelial cells, but also to exhibit activity of activating the transcription of XBP1 in vitro.
MALT1 dimerization hybrids with a gyrase B or helix loop helix domain, as well as multiple FKBP (FK506-binding protein) domains were shown to exhibit activity and NF-κB activation in cell transfection experiments [ 6, 9, 34].
All catalysts exhibit activity towards dry reforming of methane.
These tools rely on diverse mechanisms and exhibit activity in several organisms.
In the studied competitive assay conditions, all tested caspases except caspase 2 exhibit activity toward more than one substrate.
Furthermore, some comets exhibit activity in the near-nuclear region of coma in the form of jets, the polarization of which can be higher (Hadamcik et al., 2013).
Compounds in this class have been reported to exhibit activity against the human immunodeficiency virus (HIV), but their molecular target had not been identified.
In addition, multi-specific or promiscuous enzymes exhibit activity toward a wide range of substrates so as to increase cell evolvability and robustness.
An ever-increasing number of ligands is reported that exhibit activity through multiple receptors, binding in allosteric sites, and bias towards different intracellular signalling pathways.
An enzyme from the amidohydrolase family from Deinococcus radiodurans (Dr-OPH) with homology to phosphotriesterase has been shown to exhibit activity against both organophosphate (OP) and lactone compounds.
In the polymerization of ethylene, the silica-supported TAC-CrCl3 catalysts exhibit activity values from 200 to 374 kg/molCr/h with Stöber silica being the best.
