Several years ago, we used CLSM for first time to determine changes in cyanobacterial populations, because this technique avoids the use of long and exhaustive protocols, allows accurate and non-destructive optical sectioning giving results where out-of-focus images were virtually eliminated.
We have shown molecular dynamics simulations can be combined with virtual peptide screening to obtain an exhaustive docking protocol that incorporates dynamic fluctuations in a receptor.
More recently, [20] and [21] have investigated the beamforming codebook design for millimeter systems and demonstrated its superiority over the exhaustive searching protocol.
The simultaneous fitting of components is difficult as the large search space makes an exhaustive search protocol that uniformly samples over all degrees of freedom computationally unfeasible.
MMR was then estimated using an exhaustive chase protocol followed immediately by measurement of excess post-exercise oxygen consumption using intermittent flow-through respirometry (electronic supplementary material; [ 4]).
Extraction procedure E1 is an exhaustive extraction protocol previously developed by our research group [ 35], and it has previously been used for the determination of PAHs in diesel SRMs [ 34, 36], whereas extraction procedures E2 and E3 are adopted from a recent paper from NIST using PLE for the extraction of PAHs and nitro PAHs from air and diesel PM SRMs [ 36].
Treatment with allopurinol or its active metabolite oxypurinol, which blocks XO activity by binding at its active site (55), has been associated with a decrease in the levels of indicators of oxidative damage and markers of muscle damage after exhaustive exercise protocols in humans and rats (14, 16).
They are exacting and exhaustive, full of protocols and standards that might seem pretentious, even strange.
To check practical collision resistance of the relatively short 37-bit second block of InChIKey, we used the simple protocol of exhaustive direct testing.
Although this is a major limitation in a docking protocol, the exhaustive search algorithm of docking programs has been successful in predicting correct binding geometries of known hits [48].
