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"Essentially, Neanderthals were eventually left in a genetically exhausted state," said Martinón-Torres.
In the face of persistent antigen, chronic T cell receptor signaling drives T lymphocytes to a functionally exhausted state.
Even in the normal exhausted state of overtime, the Spanish knew how to exploit the extra space on the field.
Even in her exhausted state, she refused to consent, still clinging to the hope of a normal delivery.
The cycle of protest and crackdown, by then five months long, now seven, had worn into a groove of tension, an exhausted state of adrenaline and fear.
Neither gave any sign of seeking any accommodation that might pull this fractured, exhausted state back from the brink of a political crisis.
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However, it remains unknown whether T cells in human cancer adopt a similar spectrum of exhausted states based on PD-1 expression levels.
"It would be grossly unfair for us as a government to intervene in the judicial processes of another country before those processes had been exhausted," states Foreign Officer minister Baroness Amos.
Others need so much remedial work that they will exhaust state and federal student aid without ever getting a degree.
His path has been long partly because of the inevitable delays in our court processes and partly because of the requirement that he exhaust state remedies.
The Indiana Supreme Court affirmed the conviction in Irvin v. State, 236 Ind .384, 139 N.E.2d 898, and we denied direct review by certiorari 'without prejudice to filing for federal habeas corpus after exhausting state remedies.' 353 U.S. 948, 77 S.Ct.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com