Sentence examples for exerts its anticancer from inspiring English sources
It exerts its anticancer effects through the inhibition of thymidylate synthase and the incorporation of its active metabolites, into RNA and DNA so as to influence the uracil metabolism and has been used in Phase II trial of combination chemotherapy for advanced cancers of the gallbladder[ 19, 20].
It was recently shown that silibinin exerts its anticancer effects via multiple molecular mechanisms that could block all stages of carcinogenesis, including initiation, promotion, and progression, and its possible usefulness as a preventive and therapeutic agent in cancer therapy has been authenticated [ 13].
Salinomycin exerts its anticancer effects through the generation of ROS, and it also sensitizes anticancer drug- and radiation-treated cancer cells by increasing DNA damage.
Our findings suggest that EOPK exerts its anticancer activity via the inhibition of PAK1 expression, suggesting it may be a potent chemotherapeutic agent for colorectal cancer.
Paclitaxel, a microtubule-targeted anti-cancer drug exerts its anticancer effects by causing abnormal stabilization of the dynamic microtubule polymerization leading to the failure of mitotic cell cycle and induction of apoptotic cell death (Alexandre et al. 2007).
Previous studies indicated that bortezomib exerts its anticancer function by inhibiting protein degradation in cancer cells [22].
Tanshinone II was reported to exert its anticancer effect by increasing [Ca2+]i concentration to induce apoptosis in CNE cells [ 29].
Isofuranonaphthoquinone was possibly exerting its anticancer activity on Jurkat cells by generating ROS which resulted in cell death.
Retinoic acid receptors are not mutated in cancer cells, so ATRA could potentially exert its anticancer effects in many malignancies.
The study also showed that isofuranonaphthoquinone could be exerting its anticancer activity by generating reactive oxygen species resulting in cell death.
Given that dovitinib may exert its anticancer effects either by directly targeting FGFRs or regulators of angiogenesis, endometrial cancer patients with or without FGFR2 mutations are separately enrolled in a clinical to prove its mechanisms of functions [ 166].
