Sentence examples for exerts its affects from inspiring English sources

Importantly, the genetic efficiency determinant not only exerts its affects within the tumour cell itself, but also in the primary tumour stroma as well as the microenvironment at distant sites.

Overall, this study provides a detailed overview of the response to exogenous gliotoxin in resistant and sensitive A. fumigatus strains, enhances our understanding of the manner in which gliotoxin exerts its affects as a toxin, and provides a unique glimpse into cross-talk between apparently unrelated secondary metabolite gene clusters.

Significantly, however, it is thought that oxyntomodulin, differing from glucagon only through an eight-amino acid C-terminal extension, exerts its affects, in mammalian cells primarily via the GLP-1 receptor, acting to reduce food intake in humans (Wynne et al., 2005; Schepp et al., 1996).

Biochemical data suggests that estrogen exerts its affect through the processing of the amyloid precursor protein to beta-amyloid which is deposited in the brains of patients with AD.

However, there are two independent reports that showed that the tiny uORF of SAMDC is functional [ 27, 59], although there is controversy regarding the type of effect and conditions under which the tiny uORF of SAMDC exerts its affect on downstream translation.

To begin to address how pyruvate might be exerting its affects on substrate regulation, the phosphorylation of PDH, the protein content of MCD, and the activity of SirT1 were determined.

SB-431542 is another small molecule inhibitor exerting its affect through a highly specific interaction with ALK5 kinase.

Secondly, MISO may exert its affect by inhibition of the repair of cross-links or monoadducts at early times post-injection, which would not be observed in this study.

Taken together, results suggest that 7-hydroxy-3,4-dihydrocadalin exerts its antihyperalgesic affect through activation of 5-HT1 receptors and guanylyl cyclase enzyme, but not opioid receptors.

These same data point out that TGF-β is likely to exert its inhibitory affects on satellite cells through the local muscle niche or when tissue is wounded and platelets release this cytokine [ 17].

Our results indicate that silvestrol is a potent anti-cancer compound in vivo that exerts its activity by affecting survival pathways as well as angiogenesis.