Cyclooxygenase (COX) I and II catalyze the metabolism of arachidonic acid (AA), resulting in the formation of prostaglandins (PGs), thromboxanes, and hydroxyeicosateraenoic acids (HETEs) [1] [4], which exert an array of important biological actions in the body [5] [7].
Our finding of increased risk among African Americans for preterm delivery suggests that PAHs might exert an array of biologic effects in the developing fetus.
As a dietary additive they exert an array of beneficial effects on human health ranging from protection against the development of colon cancer and inflammatory bowel disease, improved calcium absorption, reduction of serum lipids and diminishing adverse effects of intestinal pathogens [ 3].
TP53 exerts a vast array of extranuclear functions and therefore the cytoplasmic pool of TP53 cooperates with its nuclear counterpart to activate programmed cell death in response to certain cellular stresses.
In addition, this extensive diversity means that, at both the individual as well as the population level, the human immune response exerts a complex array of evolutionary selective pressures driving viral evolution [13], [14] in equally intricate, sometimes even conflicting [15], [16] ways.
Multiple lines of evidence suggest that PACAP exerts a large array of pharmacological effects and biological functions.
Gen is also a principal chemopreventive component of soy and exerts a wide array of chemopreventive activities in each stage of multistep carcinogenesis [ 20, 21].
Extensive research in recent years has revealed that LLO exerts a wide array of biological activities, during the infection by LM or by itself as recombinant antigen.
In this regard, RES, a phytoalexin found in grapes and peanuts hat has shown promise as a novel chemotherapeutic agent, which exerts a wide array of biological effects, including anti-inflammatory, anti-proliferative and potential chemopreventive activity against human cancer[ 40].
Most herbicides and other pesticides exert a diverse array of immunotoxic effects on exposed individuals, including compromised humoral and cellular immunity (Banerjee et al. 1996; Rodgers 1995; Vial et al. 1996; Voccia et al. 1999).
