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Each of the 108 genetic markers exerts a weak effect, the researchers report, but collectively they are potent.
Retinoic acid (RA) exerts a weak transactivation through a RARE (retinoid acid responsive element) sequence in the CYP1A1 promoter [9], but essentially inhibits AhR activity through SMRT displacement [10], [11].
Based on our data we cannot rule out the possibility that either SNP exerts a weak effect that requires larger sample numbers for detection or that cannot be observed during the first years of disease.
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Propionic acid degradation is largely inhibited during periods of high activity of the butyric acid-converting bacteria, whereas acetic acid exerts a weaker influence on the conversion of propionic acid [59].
As previously described by Mehlotra et al. [9], we did not observe a strong reduction of heterozygosity in the CQ resistant parasite population, underlining that drug pressure from CQ treatment exerts a weaker selection on Pfmdr-1 than on Pfcrt.
Moderation indicates, for example, that a risk factor (e.g., genotype) exerts a weaker effect in the presence of another factor (e.g., social support) than in its absence.
As the article notes, gas prices do seem to exert a weak influence on voting behavior.
In contrast, pectinase addition exerted a weak effect on immediate turbidity reduction, but effectively decreased the turbidity development during storage.
But Fresnel realized that any such medium could, in effect, exert a weak pull on light and change its speed by moving, too.
Further analyses indicated a very limited sensitivity of the individual SAR scenes to differences in forest composition, although soil properties in nonflooded areas exerted a weak but nevertheless important influence on backscatter.
The genetic analysis using TagSNPs in the five genes included in the adiponutrin gene family revealed that some variants within these genes exert a weak but significant effect on obesity in children and adolescents.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com