Sentence examples for exerting a major effect from inspiring English sources

In contrast to statins, the inhibition of SS results in selective cholesterol downregulation without exerting a major effect in the isoprenylation of proteins [82].

Climate change is exerting a major effect on Mediterranean marine biodiversity through seawater warming [e.g., [366] [372]].

Thus, the palaeoenvironmental changes associated with the T-OAE event bear a minor incidence on the macrobenthic tracemaker community at the level of extinctions and changes in diversity or abundance; yet they exert a major effect on the behaviour and palaeobiology of tracemakers.

Anthropogenic climate change has likely exerted a major effect on amphibian declines.

stems were clipped at this site, we speculated that mammalian herbivores could exert a major effect on C.r.l.

These results indicate that the ERK1/2 activation achieved with 5 to 20 ng/ml LIF does not exert a major effect on Stat3 activation in HC11 cells.

These results implied that the MT exerted a major effect on β-carotene accumulation via the down-regulation of downstream genes, especially bch.

The acetyl group at the N terminus, therefore, seems to play an important role, in metabolic processes leading to the production of PpIX, whereas masking the C terminus as a methyl ester does not exert a major effect.

Thus, through the production of PAPP-A, the placenta can exert a major effect on the growth of tissues through hydrolysis of IGFBPs and release of bound IGF-1.

Third, proteins belonging to the Bcl-2 family, which are known to exert a major effect on the apoptosis-associated functional and structural impairment of mitochondria, strongly influenced sorbitol-induced apoptosis.

We were unable to detect differences in oxygen consumption under basal conditions (i.e. without inhibitors) in AOX-expressing flies, suggesting that AOX does not exert a major effect on respiration in vivo.