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However, pressure is more likely to be related to diet quality generally than weight specifically because it is often exerted to ensure that healthy foods are consumed.
CLC Sequence Viewer 6.5.2 was exerted to align sequences.
The electrostatic effect exerted by specifically adsorbed electroinactive ions upon electrode processes is accounted for by introducing into the Frumkin equation the average potential at the position occupied by the reacting particle in the transition state.
Importantly, an agent with such a large range of targets is unlikely to exert its effect specifically on a particular subset of cells, such as cancer cells, thereby suggesting to re-evaluate the potential of siramesine and its analogues as drugs, and of sigma-2 receptors as targets, in anticancer therapy.
Perhaps future work will highlight whether mRNAs encoding ribosomal proteins are locally translated and if so whether ribosomal proteins can exert functions specifically adapted to the physiology of the axon and growth cone.
Consequently, the effect of HB-19 is exerted differentially and specifically via the cell surface expressed nucleolin, which eventually becomes degraded causing reduction of cytoplasmic pools of nucleolin [28].
We have also demonstrated that VEGF directly suppresses the activation of peripheral blood T cells from ovarian cancer patients and healthy individuals, and that this effect is exerted specifically via VEGFR-2 (Ziogas et al, 2012).
Consequently, the effect of HB-19 is exerted differentially and specifically via the cell surface expressed nucleolin [ 10, 26].
This hypothesis is supported by two main observations: (1) the effects of 7-keto cannot be mimicked by other cholesterol oxides such as 25-OH and (2) the effects of 7-keto are exerted specifically on Cx43 as the endocytic pathway is not inhibited (internalisation of dextran is not diminished).
While conventional maximum tolerated dose (MTD) chemotherapy exerts only mild and reversible anti-angiogenic effects, low-dose metronomic (LDM) chemotherapy was developed to specifically target tumour angiogenesis.
We designed siRNA to specifically target Smad2.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com