Whereas the genetic class is assumed to be stable over time, circumstantial factors are susceptible to change but exert only a small effect.
The contribution of ER phosphorylation at individual sites is generally underexplored, although phosphorylation of either ser or ser in the AF1 domain of ERα can exert only a small effect on gene transcription [ 69]; hence, the significance of ERser167 inhibition with AZD8055 in TamR and MCF7-X cells remains unclear.
Therefore, the pennate muscle can exert a greater force but cannot shorten a great deal; the parallel-fibred muscle can exert only a relatively small force but can shorten significantly.
This last factor exerts only a small influence.
In addition, increasing the power exerts only a small effect on the TRP, compared to conducting a replication study, which is reflected in the small elevation of the TRP curve upon increasing the power, as compared to much larger shift in the event of conducting replications.
This pattern might be realized if at the start of every host-generation, the parasite population is small (and hence exerts only a negligible selection on the host-population) and later, after a number of parasite generations, reaches an appreciable size (and thus exerts appreciable selection on the host after it has adapted to the host population).
Consequently, mud crabs presumably exert only a weak predation pressure on D. polymorpha.
If each of the genes responsible for healthy aging exerts only a modest effect, the 100 person project may be too small to pick them out.
The unbrushed SCF exerts only a minor adhesion force on the colloidal probe (Fig. 2a), and accordingly the friction forces are small (Fig. 2b).
Exposure to anti-androgens, which individually appears to exert only small effects, may induce marked responses in concert with, possibly unrecognized, similarly acting chemicals.
