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These complications occurred due to the expansion force that was exerted mainly on the teeth and inability to overcome maxillary osseous suture resistance.

From a competition perspective, the most challenging problem in laser source manufacturing is price pressure, a result of cost competition exerted mainly from Asia.

In general, climate change affects runoff not only by changing the hydrological inputs (precipitation and potential evaporation) but also by altering the watershed characteristics as represented by the parameter w; while the impacts of human activities on runoff are exerted mainly through the alteration of the watershed characteristics.

The present results favor the view that the adverse effects of chronic exposure to FFA is exerted mainly through the newly discovered FFA receptor GPR40 by inducing expression and activity of β-cell iNOS, a highly increased NO generation, and suppression of glucose-stimulated insulin release.

However, no significant inhibition of HIV replication was observed with supernatants from any group of unstimulated pDCs (Figure 3B), suggesting that the suppression depicted in Figure 2B by unactivated pDCs was exerted mainly through a cell-mediated mechanism unlikely to be mediated solely by IFN-α.

iNKT cells display a powerful helper activity for adaptive T as well as B cell responses, exerted mainly via enhancing antigen presenting functions in DC [10], [11], which result in facilitated priming of peptide-specific CD4+ and CD8+ T cell responses.

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Sulforaphane, an isothiocyanate compound of cruciferous vegetables, also exerts mainly anti-inflammatory properties on immune processes.

Accordingly, such systems have little influence on the level of oxygenation, while they exert mainly a positive action by the mean of CO2 removal.

These M2-type macrophages exert mainly anti-inflammatory effects through mediators such as transforming growth factor-beta [ 31].

SDF-1/CXCL12 is a unique CXC chemokine as it exerts mainly a homeostatic function, yet it has been implicated in inflammation such as in RA [ 13, 14, 17, 29].

In the NMRI nu/nu mice, which did not mount a cellular immune response of graft rejection, thalidomide exerted a mainly anti-angiogenic effect.

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