Sentence examples for exerted its role from inspiring English sources

The results demonstrated that Glu11 exerted its role of binding site through forming H-bond by the interaction of its side chain with the Lys anchor in the frame of TP5 (Fig. 7A, C).

As we have shown that Dok6 works as a substrate of the TrkC receptor in mouse brain, next we investigated whether Dok6 exerted its role in cortex neuron neurite outgrowth through the NT-3/TrkC pathway.

Hence it is involved in the binding specificity of Ir-LBP and plays a key role in ligand binding as confirmed by mutational analysis (which also showed that it exerts its role in cooperation with Arg 53).

When SPARC is secreted from stroma cells, it exerts its role on neoplastic progression in a paracrine fashion (Porte et al, 1995; Le Bail et al, 1999).

Alternatively, it is possible that maspin exerts its role only in the nucleus at the level of gene or chromatin regulation and thus indirectly affects the cell-matrix interaction or differentiation state and is released only as a consequence of cell damage or necrosis [20 27].

Mutation of p21WAF1/CIP1 is rare in different types of human malignancy, therefore, it is suggested that p21WAF1/CIP1 exerts its role in tumorigenesis mainly on expression level.

It is possible that ETK may exert its role in bladder cancer through regulating these pathways.

NapA is directly activated by oxidation through ROS, allowing it to enter the nucleus and exert its role as a positive transcription factor.

In fact, it was observed in both animal models of bleomycin-induced fibrosis and in lung tissues of IPF patients that HIF 1- α is overexpressed and may exert its role in early stages of fibrogenesis as it was localized in areas of active fibrosis and in normal areas of IPF lung but not within the fibroblastic foci which represent areas of established fibrosis [ 42].

Cr is a key factor in determining the passive current of the alloy; whereas, in the transpassive region, Mo exerts its role by inhibiting the local dissolution of metals via attachment to the outermost surface of the chromium oxide film.

Our results suggest that Plk2 exerts its role in centrosome duplication by phosphorylating NPM/B23 on S4.